This study aimed to optimize the site selection of artificial groundwater recharge zones in the Yazd-Ardakan watershed (covering an area of 116,765 hectares) to address challenges such as water scarcity, severe groundwater depletion, and annual rainfall below 100 mm. The research integrated Geographic Information Systems (GIS) and Multi-Criteria Decision-Making (MCDM) methods. Seventeen influential criteria, including elevation, slope, land use, geology, soil type, climate, distance from faults, and isothermal lines were analyzed using ArcGIS 10.5. Criteria weighting was performed using the Best-Worst Method (BWM), and layer integration was achieved through the Weighted Linear Combination (WLC) approach. Results indicated that slope (weight: 0.203), elevation (correlation >0.75), and land use (correlation ≈0.5) had the highest impact on zone suitability, while climate and isothermal lines were less influential. The final suitability map (900×900 m resolution) revealed that central and southern plain areas with slopes <2%, permeable alluvial formations, flat topography, and optimal distance from faults were prioritized for artificial recharge. Sensitivity analysis identified eight key criteria (correlation >0.5), and by eliminating 53% of non-essential parameters, an efficient framework for sustainable water resource management was established. This study not only contributes to raising groundwater levels, improving soil fertility, and preserving local ecosystems but also offers a practical solution for water crisis management in arid regions.