Muteh wildlife refuge, with an area of about 220,000 ha, is situated at 95 km north of Isfahan. In this refuge, 511 species of vascular plants belonging to 284 genera and 59 families live along with 117 species of vertebrate animals belonging to 84 genera and 37 families.

 Rare plants of the area were classified into two categories of “endangered” and “vulnerable” according to IUCN, 1996 categories. The endangered species include Astragalus chaetopodus Bunge. Astragalus eriostomus Bornm. Astragalus indistinctus Podl. and Maassoumi Cousinia phyllocephala Bornm. and Gauba Cousinia rhaphiocephala Rech. f. Cousinia straussii Hausskn. and C. Winkl. Ferula kashanica Rech. f. Onobrychis psoraleifolia Boiss. var. Psoraleifolia and var. pleiophylla Bornm. The vulnerable species include Bunium caroides (Boiss.) Hausskn. ex Bornm. Dielsiocharis kotschyi (Boiss.) O. E. Schultz Dionysia caespitosa (Duby) Boiss. Dorema ammoniacum D. Don. Dorema aucheri Boiss. Dracocephalum kotschyi Boiss. Echinophora platyloba DC. Hymenocrater bituminosus Fisch. and C. A. Mey. Pimpinella deverroides (Boiss.) Boiss. Prangos cheilanthifolia Boiss. and Thymus daenensis Celak subsp. daenensis.

 The rare animal species of the region were classified into four categories: “critically endangered”, “endangered”, “vulnerable”, and “conservation-dependent species”. The critically endangered species are Felis silvestris Schreber F. caracal Schreber Jaculus blanfordi Murray (mammals) Gypaetus barbatus Falco pelegrinoides F. cherrug and F. peregrinus (birds). The endangered species include Vulpes cana Blanford Ochotona rufescens Gray (mammals) Falco naumanni F. columbarius Chlamydotis undulata (birds) and Varanus griseus (reptilian). The vulnerable species are Gazella subgutturosa Guldensteadt Canis lupus Linnaeus Meles meles Linnaeus Hyaena hyaena Linnaeus (mammals) and Aquila chrysaetos (bird). And, finally, the conservation-dependent species include Ovis orientalis Linnaeus Capra aegagrus Elxleben Panthera pardus Linnaeus (mammals) and Ammoperdix griseogularis (bird). The results from this survey were compared with the findings from the survey of some other protected areas in Iran.